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1例71岁男性患者因右肺癌切除术后化疗,给予双环铂650 mg加入5%葡萄糖注射液1000 mL静脉滴注,4 h内输注完毕。次日,患者出现双下肢无力,恶心。3周后患者行第2次化疗,方案与第1次相同。次日,患者出现恶心、右侧鼻腔出血。实验室检查:WBC 3.04×109/L,N 0.50,L 0.37,Hb 83 g/L,RBC 2.76×1012/L,PLT 35×109/L。立即行鼻腔局部止血等对症治疗。3 d后鼻腔出血消失,血常规逐渐恢复正常,实验室检查:WBC 4.04×109/L,N 0.53,L 0.35,Hb 86 g/L,RBC4.16×1012/L,PLT 87×109/L。
A 71-year-old male patient undergoing chemotherapy after right lung resection was given an intravenous infusion of 650 mg of bicycloplatin and 1000 mL of 5% glucose injection, and the infusion was completed within 4 h. The next day, patients with weakness, nausea and lower extremities. After 3 weeks, the patient received the second chemotherapy, the same protocol as the first one. The next day, the patient developed nausea, right nasal bleeding. Laboratory tests: WBC 3.04 × 109 / L, N 0.50, L 0.37, Hb 83 g / L, RBC 2.76 × 1012 / L, PLT 35 × 109 / L. Immediate nasal local hemostasis and other symptomatic treatment. After 3 days, nasal hemorrhage disappeared and blood routine gradually returned to normal. Laboratory tests showed that WBC 4.04 × 109 / L, N 0.53, L 0.35, Hb 86 g / L, RBC 4.16 × 1012 / L, PLT 87 × 109 / L .