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报道甲状腺粘膜相关淋巴瘤12例,淋巴性甲状腺炎6例。淋巴性甲状腺炎分为轻、中、重三级。研究上述18例有免疫组化结果的资料,发现粘膜相关淋巴瘤多见于老年女性,并从淋巴细胞性甲状腺炎发展演变而来,以中心细胞样细胞为多见,免疫组化示B-细胞性单克隆性。组织病理学上常形成淋巴上皮病变,瘤栓样或戒指样结构。本文探讨了淋巴性甲状腺炎与甲状腺粘膜相关淋巴瘤的发病机理、鉴别诊断及治疗方法的选择等。
Reported 12 cases of thyroid mucosa-associated lymphoma, 6 cases of lymphatic thyroiditis. Lymphoid thyroiditis is divided into light, medium and heavy grades. Study of the above 18 cases of immunohistochemical results, found that mucosa-associated lymphoma is more common in older women, and evolved from the development of lymphocytic thyroiditis, central cell-like cells are more common, immunohistochemistry B-cells Monoclonality. Histopathologically, lymphoid epithelial lesions, tumor thrombi-like or ring-like structures are often formed. This article explores the pathogenesis, differential diagnosis, and treatment options of lymphoid thyroiditis and thyroid mucosa-associated lymphoma.