萘普酮是一种非酸性非甾体抗炎药物,该药经胃肠吸收后再转化为有抗炎作用的代谢物,因而有较好的安全性。我们用国产萘普酮与其他几种抗炎药相比,研究了萘普酮的毒性与亚急性毒性,实验结果如下: 萘普酮对大鼠口服急性LD_(50)为2896mg/kg,小鼠急性口服LD_(50)为6788mg/kg,而消 Nadropone is a non-acidic, non-steroidal anti-inflammatory drug that is absorbed safely by the gastrointestinal tract and converted to metabolites that have anti-inflammatory properties and thus have good safety. We use domestic napephone compared with several other anti-inflammatory drugs, studied the toxicity and subacute toxicity of napephone, the experimental results are as follows: The oral administration of nadropan in rats LD50 (50) of 2896mg / kg, small Rats acute oral LD_ (50) 6788mg / kg, and eliminate