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为探讨米非司酮配伍前列腺素终止早孕的剂量及服用方法,对1035例妊娠≤49天的妇女,按服用米非司酮不同剂量,一次服用200mg或150mg,和分次服用150mg或125mg,并于第三或四天配伍卡前列甲酯栓或米素前列醇,分为8组,观察终止妊娠效果。结果:8组中,除一次服用米非司酮150mg外,其它各组的完全流产率均为92%以上。应用前列腺素后排出胎囊的时间,米索前列醇比卡前列甲酯栓为短;胃肠道反应,米索前列醇比卡前列甲酯栓为轻。提示:一次眼用米非司酮,必需服用200mg才可达到90%以上的流产效果。
To explore the dose of mifepristone with prostaglandin and to terminate early pregnancy, 1035 women with pregnancy less than 49 days were given different doses of mifepristone, 200 mg or 150 mg at a time, and 150 mg or 125 mg at a time. And in the third or four days compatibility card forefront of methyl ester suppositories or misoprostol, divided into 8 groups, observe the effect of termination of pregnancy. Results: In the 8 groups, the complete miscarriage rate of all the other groups was over 92% except for taking 150 mg of mifepristone once. Application of prostaglandin after the discharge of fetal time, misoprostol card than methyl thiazole suppository short; gastrointestinal reactions, misoprostol card than methyl thiazole suppository. Tip: an ophthalmic mifepristone, must take 200mg to achieve more than 90% of the abortion effect.