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目的:观察神效栝蒌散联合化疗方案在晚期乳腺癌新辅助化疗中的疗效和毒性反应。方法:64例晚期乳腺癌患者随机分为对照组和治疗组,对照组接受TA化疗方案;治疗组在对照组的基础上加服神效栝蒌散每21天为1个疗程,共行2个疗程。结果:从总临床客观缓解率和主要不良反应上看治疗组明显优于对照组。结论:神效栝蒌散联合西药化疗方案对晚期乳腺癌患者而言是一个很好的治疗方案。
OBJECTIVE: To observe the efficacy and toxicity of Shenxiao Jieyu Powder combined with chemotherapy in neoadjuvant chemotherapy of advanced breast cancer. Methods: Sixty-four patients with advanced breast cancer were randomly divided into control group and treatment group. The control group received chemotherapy regimen of TA. On the basis of the control group, the treatment group was treated with Shenxiao Yizhona Powder once every 21 days for 2 courses Course of treatment. Results: From the total clinical objective response rate and the main adverse reactions in the treatment group was significantly better than the control group. Conclusion: Shenxiao Juban San combined with Western medicine chemotherapy for patients with advanced breast cancer is a good treatment.