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对醋氨己酸锌的抗实验性动物胃溃疡作用进行了研究.结果表明:醋氨己酸锌显著抑制小鼠水浸应激性胃溃疡的形成.对无水乙醇所致的大鼠胃粘膜损伤具有明显的保护作用.且显著减轻幽门结扎大鼠胃粘膜的损伤.同时,对大鼠幽门结扎后6h的胃液进行分析,300mg/kg醋氨己酸锌增加胃液分泌量,降低游离酸和总酸量.醋氨己酸锌并具有抑制胃蛋白酶活性的作用.
The anti-experimental animal gastric ulcer effect of zinc acetimidate was studied. The results showed that zinc acetohexanoate significantly inhibited the formation of gastric ulcer induced by water immersion in mice. On ethanol-induced gastric mucosal injury in rats with significant protective effect. And significantly reduce gastric mucosal injury in pylorus ligation rats. At the same time, gastric juice was analyzed 6 h after pyloric ligation in rats, and 300 mg / kg zinc acylamino caprate increased gastric juice secretion and decreased free acid and total acidity. Zinc carbaminate and has the effect of inhibiting pepsin activity.