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氟啶酸是一种新型广谱喹诺酮类抗菌剂,在试管内,抗奈瑟氏淋球菌(NG)活性:PPNG和NPPNG菌株MIC_(90)<0.66μg/ml。作者报道多中心对比研究氟啶酸和头孢三嗪治疗无并发症淋病的疗效。 152例病人随机接受氟啶酸和头孢三嗪治疗。77例一次口服氟啶酸400mg,另75例一次肌注头孢三嗪250mg。其治愈率:氟啶酸组,尿道淋病为98%、宫颈和直肠淋病为
Fluoric acid is a novel broad-spectrum quinolone antibacterial agent that has anti-Neisseria gonorrhoeae (NG) activity in test tubes: MIC 90 (90) <0.66 μg / ml for PPNG and NPPNG strains. The authors report a multicenter comparative study of the efficacy of fluorotinic acid and ceftriaxone in the treatment of non-complication gonorrhea. 152 patients were randomized to receive fluorometacin and ceftriaxone. 77 cases of oral fluorosis acid 400mg, another 75 cases of intramuscular ceftriaxone 250mg. The cure rate: fluorosis group, urinary tract gonorrhea 98%, cervical and rectal gonorrhea