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一、人类线粒体ＤＮＡ(ｍｔＤＮＡ)序列分析和应用的历史沿革1 981年Ａｎｄｅｒｓｏｎ完成了人类线粒体基因组的全部核苷酸序列的测定 ,并提出人类ｍｔＤＮＡ呈闭合环状 ,总长度为 1 6 5 6 9ｂｐ[1 ] 。在此基础上 ,许多学者致力于分析这一环状小分子ＤＮＡ ,以揭示ｍｔＤＮＡ
I. History of human mitochondrial DNA (mtDNA) sequence analysis and application In 1981, Anderson completed the determination of the complete nucleotide sequence of human mitochondrial genome and proposed human mtDNA was closed loop with a total length of 1 6 5 6 9 bp [1 ] . On this basis, many scholars devoted themselves to analyzing this circular small molecule DNA to reveal mtDNA