瘙痒是维持性血液透析患者最常见的皮肤表现,虽不威胁生命,但却严重影响患者的生活质量。20世纪70年代,Nielsen等[1]报道终末期肾衰竭患者难治性瘙痒的发生率为85%。近20 Pruritus is the most common skin manifestation of maintenance hemodialysis patients, although it does not threaten the life, but seriously affects the quality of life of patients. In the 1970s, Nielsen et al. [1] reported that the incidence of refractory pruritus in patients with end-stage renal failure was 85%. Nearly 20