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目的对腹腔镜下根治术与经腹直肠癌根治术在大肠癌治疗中的疗效进行比较,为临床手术方式的选择提供参考。方法 87例择期手术治疗的大肠癌患者为研究对象,随机分为观察组(44例)和对照组(43例)。观察组予以腹腔镜下根治术,对照组予以经腹直肠癌根治术。比较两组患者的手术切口长度、术后疼痛指数、淋巴结清扫数目、并发症及生存质量。结果观察组手术切口长度为(6.8±2.3)cm,短于对照组的(10.5±2.6)cm,差异具有统计学意义(t=7.035,P<0.05);观察组术后疼痛指数为(4.3±1.2),低于对照组的(6.8±1.4),差异具有统计学意义(t=8.950,P<0.05);观察组淋巴结清扫数目为(15.5±3.6)个,对照组为(15.8±3.5)个,比较差异无统计学意义(t=0.394,P>0.05);观察组并发症发生率为9.1%(4/44),低于对照组的25.6%(11/43),差异具有统计学意义(χ2=4.145,P<0.05)。观察组生存质量评分为(125.6±4.3)分,高于对照组的(113.5±3.7)分,差异具有统计学意义(t=14.055,P<0.05)。结论在大肠癌的治疗中腹腔镜下根治术较经腹直肠癌根治术具有创伤小、并发症少、痛苦度小及术后生存质量高等优势,具有临床推广价值。
Objective To compare the curative effects of laparoscopic radical mastectomy and transabdominal radical mastectomy in the treatment of colorectal cancer and provide references for the selection of clinical surgical modalities. Methods 87 cases of patients with colorectal cancer undergoing elective surgery were randomly divided into observation group (44 cases) and control group (43 cases). The observation group underwent laparoscopic radical mastectomy and the control group underwent radical mastectomy. The surgical incision length, postoperative pain index, number of lymph node dissection, complications and quality of life were compared between the two groups. Results The length of surgical incision in the observation group was (6.8 ± 2.3) cm, shorter than that in the control group (10.5 ± 2.6) cm, the difference was statistically significant (t = 7.035, ± 1.2) and lower than the control group (6.8 ± 1.4), the difference was statistically significant (t = 8.950, P <0.05). The number of lymph node dissection in the observation group was (15.5 ± 3.6) ), The difference was not statistically significant (t = 0.394, P> 0.05). The complication rate in observation group was 9.1% (4/44), which was lower than that in control group (25.6%, 11/43) Significance (χ2 = 4.145, P <0.05). The quality of life in the observation group was (125.6 ± 4.3) points higher than that in the control group (113.5 ± 3.7) points, the difference was statistically significant (t = 14.055, P <0.05). Conclusion In laparoscopic radical mastectomy, laparoscopic radical mastectomy has less trauma, less complications, less pain and higher postoperative quality of life than radical mastectomy, which is of clinical value in the treatment of colorectal cancer.