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目的 :分析乳腺囊内乳头状癌的临床病理特征、预后及治疗。方法 :收集49例乳腺囊内乳头状癌的临床资料和随访资料,分析其临床病理特征,并探讨不同临床病理特征对预后的影响。结果 :49例乳腺囊内乳头状癌患者的中位年龄为64岁(范围:29~79岁)。中位随访时间为61个月(范围:24~84个月)。5年总生存率为75.0%,5年无病生存率为60.6%。保乳手术组12例患者的5年总生存率为76.9%,乳房全切组37例患者的5年总生存率为73.8%,2组的差异无统计学意义(P=0.935)。结论 :乳腺囊内乳头状癌是一种非常少见的乳腺癌类型,预后较好。保乳手术和乳房全切术均可作为乳腺囊内乳头状癌的手术治疗方式。
Objective: To analyze the clinicopathological characteristics, prognosis and treatment of papillary carcinoma in cyst. Methods: The clinical data and follow-up data of 49 cases of intraductal papillary carcinoma of the breast were collected. The clinical and pathological features were analyzed, and the influence of different clinicopathological features on the prognosis was discussed. Results: The median age of 49 patients with intraductal papillary carcinoma was 64 years (range: 29-79 years). The median follow-up time was 61 months (range: 24-84 months). 5-year overall survival was 75.0%, 5-year disease-free survival rate was 60.6%. The 5-year overall survival rate of breast-conserving surgery group was 76.9%. The 5-year overall survival rate of 37 patients in breast total resection group was 73.8%. There was no significant difference between the two groups (P = 0.935). Conclusion: Breast intracapsular papillary carcinoma is a very rare type of breast cancer, the prognosis is good. Breast conserving surgery and total mastectomy can be used as a surgical treatment of intraductal papillary carcinoma.