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目的:探讨肺隐球菌病的临床及影像学表现,提高对该病的认识。材料与方法:回顾分析2004年1月至2012年6月在我科行经皮肺穿刺活检术明确诊断的12例肺隐球菌患者的临床及影像学资料。结果:6例隐球菌肺炎患者临床症状较轻,表现为不同程度的咳嗽、咳痰、咳少量血丝痰、气喘、低热和胸背痛;2例隐球菌肺炎患者因合并肾功能不全、肾衰竭期临床症状较重;另4例无明显呼吸道症状。影像表现为①结节或肿块病变;②单发或多发斑片状肺实变影;③混合型病变。经皮肺穿刺术前确诊2例,10例误诊断为其它疾病,误诊率为83.33%。结论:新型隐球菌肺炎的临床症状与影像学表现通常不符,影像学对肺隐球菌的误诊率较高,经皮肺穿刺活检术是有价值的确诊手段。
Objective: To investigate the clinical and imaging manifestations of pulmonary cryptococcosis and to improve its understanding of the disease. Materials and Methods: The clinical and imaging data of 12 cases of pulmonary cryptococcosis diagnosed by percutaneous pulmonary biopsy in our department from January 2004 to June 2012 were retrospectively analyzed. Results: Six patients with cryptococcal pneumonia had mild clinical symptoms, with varying degrees of cough, phlegm, cough, phlegm, asthma, fever and chest pain. Two patients with cryptococcal pneumonia had renal insufficiency and renal failure Period clinical symptoms were severe; the other 4 cases without obvious respiratory symptoms. The image showed ① nodules or mass lesions; ② single or multiple patchy lung consolidation; ③ mixed lesions. Percutaneous pulmonary puncture before the diagnosis of 2 cases, 10 cases misdiagnosed as other diseases, misdiagnosis rate was 83.33%. Conclusion: The clinical manifestations and imaging findings of Cryptococcus neoformans pneumonia are usually not consistent. The misdiagnosis rate of Cryptococcus neoformans is high in imaging studies. Percutaneous pulmonary biopsy is a valuable diagnostic tool.