本文首次报道,用沙门氏菌的营养缺陷型细菌琼雷株作为生物杀鼠剂。以三种方法:毒饵法、鼠的同类残食法和饮水传染法,对害鼠作了毒杀效果观察。结果表明:对灰仓鼠和草原兔尾鼠的致死效果均超过95％;小家鼠70％左右;柽柳沙鼠最低。对鸡、兔、羊的安全试验表明:该菌具有相对不易感染的安全性。 This paper reports for the first time that Salmonella typhimurium auxotrophic bacteria agarics strain as a biological rodenticide. To three kinds of methods: bait method, the same kind of food residue method of mice and drinking water infection, poisoning effect on rats was observed. The results showed that the lethal effects on gray hamster and prairie rabbit were more than 95%; Mus musculus about 70%; Safety tests on chickens, rabbits and sheep show that the bacterium has a relatively insecure safety.