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目的探讨乳腺恶性肿瘤冠状面“汇聚征”与临床病理学特征间的关系。方法应用自动乳腺全容积成像技术,回顾性分析经手术病理证实的258个乳腺恶性肿瘤病灶的冠状面特征(有无冠状面“汇聚征”),并比较冠状面特征在不同年龄、病灶部位、大小、同侧腋窝淋巴结转移情况、病理类型及分化程度等临床病理学特征间的差异性。结果乳腺恶性肿瘤冠状面“汇聚征”在不同年龄、病灶部位及大小间差异无统计学意义(P>0.05);在导管原位癌不同级别(低、中级别及高级别)及浸润性导管癌不同分级(Ⅰ、Ⅱ级及Ⅲ级)间差异无统计学意义(P>0.05);浸润性乳腺癌及有同侧腋窝淋巴结转移的冠状面“汇聚征”出现率高于非浸润性乳腺癌及无淋巴结转移(P<0.05)。以乳腺恶性肿瘤患者各临床病理学特征为自变量,有无冠状面“汇聚征”为因变量进行Logistic回归分析,浸润性乳腺癌及同侧腋窝淋巴结转移为危险因素(回归系数分别为2.135、0.611;OR值分别为8.454、1.842)。结论乳腺恶性肿瘤冠状面“汇聚征”的出现率与肿瘤的浸润性及有无同侧腋窝淋巴结转移有关,可作为评价乳腺恶性肿瘤生物学行为的一项辅助指标,为临床提供参考依据。
Objective To investigate the relationship between the clinical features and the coronal “convergence syndrome” of breast malignant tumors. Methods A total of 258 breast malignancies confirmed by surgery and pathology were retrospectively analyzed with coronal features (with or without coronal “confluence”) by means of automatic breast total volume imaging. The coronal characteristics were compared between different age and lesion Site, size, ipsilateral axillary lymph node metastasis, pathological type and degree of differentiation and other clinicopathological features of the differences. Results There was no significant difference in the age, the location and the size of the lesion between the breast and the breast of the malignant breast tumor (P> 0.05). In the different grades (low, middle and high grade) There were no significant differences in different grades (Ⅰ, Ⅱ and Ⅲ) of ductal carcinoma (P> 0.05). The incidence of invasive breast cancer and coronal “convergence syndrome” with ipsilateral axillary lymph node metastasis was higher than Non-invasive breast cancer and no lymph node metastasis (P <0.05). According to the clinicopathological characteristics of patients with breast cancer as independent variables, with or without coronal “confluence” as the dependent variable Logistic regression analysis, invasive breast cancer and ipsilateral axillary lymph node metastasis as risk factors (regression coefficients were 2.135,0.611; OR values were 8.454,1.842, respectively). Conclusion The incidence of coronal “confluence” in breast malignant tumor is related to tumor invasion and metastasis of ipsilateral axillary lymph node, which can be used as an auxiliary index to evaluate the biological behavior of breast malignant tumor and provide reference for clinic .