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随着医学模式由传统生物医学模式向生物?心理?社会医学模式的转变，心理问题作为恶性肿瘤的病因已深入到临床进行研究。近几十年来行为医学研究显示：复性心理因素（如焦虑、抑郁、痛苦及紧张等）与人类一些恶性肿瘤的发生有一定关系。心理因素在恶性肿瘤治疗中的作用日益显著。负面心理情绪不仅对肿瘤病程转变造成了不良影响，而且可影响患者的生活质量。故在恶性肿瘤支持治疗的同时应加强对心理问题的关注。本文根据国内外一些文献报道，对恶性肿瘤患者心理问题方面的研究结果简要综述如下。“,”With the transformation from the traditional biomedical model to bio?psychosocial medical model, psychological problems as malignant tumor etiology have become deeply studied into clinical research. Behavioral medicine research in recent decades indicated that complex psychological factors ( such as anxiety, depression, pain, stress) have a certain relationship with the occurrence of some human malignant tumor. The role of psychological factors in treatment of malignant tumor is becoming more and more signifi?cant. Negativepsychological mood not only caused adverse effects on neoplastic disease transformation, but also can influence the quality of life of the patients. So in the malignant tumor treatment at the same time we should strengthen thesupport of psychological problems. According to some reports in the literature at home and abroad, this article makes a brief review on the psychological prob?lems of patients with malignant tumor as follows.