已知MOPP(氮芥、长春新碱、甲基苄肼、强的松)和MVPP(氮芥、长春花碱、甲基苄肼、强的松)治疗Hodgkin′s(何杰金)氏病有较好的缓解率和生存期。但毒性较大,特别是(?)芥引起恶心呕吐,常需住院并使用大剂量镇静剂。作者根据:①苯丁酸氮芥单药与氮芥单药对何杰金氏病的疗效相近。②苯丁酸氮芥与长春花碱联用对何杰金氏病可获60%的完全缓解率;③实验研究发现苯丁酸氮芥的抗瘤作用可被类 MOPP (mechlorethamine, vincristine, procarbazine, prednisone) and MVPP (mechlorethamine, vinblastine, procarbazine, prednisone) are known to treat Hodgkin’s disease Have a better response rate and survival. However, more toxic, especially (?) Mustard caused nausea and vomiting, often hospitalized and the use of high-dose sedatives. The author according to: ① chlorambucil single drug and nitrogen mustard monotherapy for Hodgkin’s disease similar efficacy. ② chlorambucil and vinblastine combined with Hodgkin’s disease was 60% complete remission rate; ③ experimental study found that chlorambucil antitumor effect can be class