云南锡业公司肺癌流行病学、病因学初步探讨

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云南的肺癌,个旧与宣威是高发病流行区,在1974—1976年全省普查癌肿死亡统计,肺癌是恶性肿瘤的第三位,三年内共死亡2.461人,死亡率2.97/10万(标化死亡率2.84/10万)占恶性肿瘤死亡率9.55%。宣威肺癌,发生在农村,由于农民,屋小人多,屋内无烟囱,农民习惯,常年在屋中央有一地炉,烧用烟煤,室内空气中,含3.4苯并蓖(简称 B.P)(芳香族多环碳氢化合物)的浓度高达559.44微克/百立方米,室外空气中 B.P 的平均浓度为18.23微克/百立方米,因妇女在家时多,故女性发病率较高于男性。个旧的情况,与宣威不同,肺癌患者为锡矿工人,锡矿工人长年工作在坑道内,长年接触放射性物质,氢及其子体,累积照射剂接近 qoo W.L.m 放射性氡,由短寿命的氡子体衰变产生的 a 粒子,形成强烈的放射灶,因而引起肺癌,这是公认的,又矿石中的含砷量较高,对于无机砷的致癌,已为大量流行学资料所肯定,但在动物实验,尚未得到阳性结果,我们初步同意他们的小结。至于吸烟,众肯定与肺癌有一定的关系,烟草中含有4000余种物质,致癌性的多达几十种,仅以 B.P 为代表的多环芳烃就有十余种,要减低肺癌发病须教育宣传群众自觉戒烟,这是必要的措施。云南工业,日趋发达,大气污染,日益严重,肺癌有上升趋势,此乃一社会问题,希望领导同志重视这一问题,我们医卫系统,对于肺癌的病因学,仍须更深一步研究,并要求要作出早期诊断,为保障工人、农民与群众健康而共同努力。 Yunnan lung cancer, Gejiu and Xuanwei is a high incidence of endemic areas in the province in 1974-1976 census of cancer death statistics, lung cancer is the third cancer, a total of 2.461 deaths within three years, the mortality rate of 2.97 / 100 000 ( Standardized death rate 2.84 / 100000) accounted for 9.55% of malignant tumor mortality. Xuanwei lung cancer occurs in rural areas. Due to the large number of peasants and villagers, there are no smokestacks in the house. Peasants habitually have a hearth in the central part of the house throughout the year, burning bituminous coal, and indoors with 3.4 g of benzoguanamine (BP) And the average concentration of BP in outdoor air was 18.23 micrograms per hundred cubic meters. Due to the large number of women at home, the incidence of females is higher than that of males. Gejiu situation, and Sherwin different, lung cancer patients for tin miners, tin miners work long years in the tunnel, for many years contact with radioactive material, hydrogen and its daughters, the cumulative radiation dose close to qoo WLm radon by the short life Of radon progeny decay produced a particle to form a strong radiation, which led to lung cancer, which is recognized, and arsenic in the ore is higher, for carcinogenic inorganic arsenic, has been a large number of popular data affirmed, However, in animal experiments, positive results have not yet been obtained, and we initially agree with their summary. As for smoking, all certainly have a certain relationship with lung cancer, tobacco contains more than 4,000 species of carcinogenic up to dozens of species, only represented by BP, there are more than 10 kinds of polycyclic aromatic hydrocarbons, to reduce the incidence of lung cancer education Publicity consciously quit smoking, this is a necessary measure. As the industry in Yunnan is becoming more and more developed with air pollution becoming increasingly serious, there is an upward trend in lung cancer. This is a social issue. We hope that leading comrades will pay attention to this issue. Our medical and health care system still needs further study on the etiology of lung cancer and requires To make an early diagnosis, to protect the health of workers, peasants and the masses and work together.
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