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机体血液中存在的凝血酶原，在血液离开血管后，经数种凝血因子作用后，转变为有活性的凝血酶。它与血液接触后，纤维蛋白原立即变成纤维状的纤维蛋白而将血细胞网住形成血块，并作为血栓堵住血管创面，而达到立即止血的目的。目前使用的止血药有些能加速血液凝固或降低毛细血
The presence of prothrombin in the bloodstream of the body, after the blood has left the bloodstream, is converted to active thrombin by several coagulation factors. When it comes in contact with blood, fibrinogen immediately becomes fibrillar fibrinogen which forms a blood clot in the blood cell network and blocks the blood vessel wound as a thrombus to achieve immediate hemostasis. Some of the currently used hemostatic agents accelerate blood clotting or reduce capillary blood flow