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目的观察阿昔洛韦联合痰热清治疗婴幼儿呼吸道合胞病毒肺炎的疗效。方法选择2006年9月~2009年5月在我科住院诊断为呼吸道合胞病毒(RSV)肺炎的婴幼儿150例,随机分为对照组、治疗Ⅰ组和治疗Ⅱ组,对照组给予利巴韦林静滴及常规抗感染、对症治疗,治疗Ⅰ组将对照组治疗方案中利巴韦林更换为阿昔洛韦,治疗Ⅱ组在治疗Ⅰ组的基础上加用痰热清治疗。结果对照组、治疗Ⅰ组、治疗Ⅱ组的总有效率分别是94%、92%、98%;治疗Ⅱ组与对照组比较有显著性差异(p<0.01),治疗Ⅱ组与治疗Ⅰ组比较有显著性差异(p<0.01),而治疗Ⅰ组与对照组比较无差异(p>0.05)。结论阿昔洛韦联合痰热清治疗婴幼儿呼吸道合胞病毒肺炎疗效显著。
Objective To observe the curative effect of acyclovir combined with Tanreqing on infantile respiratory syncytial virus pneumonia. Methods 150 cases of infants and young children diagnosed as respiratory syncytial virus (RSV) pneumonia in our hospital from September 2006 to May 2009 were randomly divided into control group, treatment group Ⅰ and treatment group Ⅱ, control group was given Liba Weileng intravenous drip and conventional anti-infective, symptomatic treatment of treatment group Ⅰ treatment of ribavirin in the control group was replaced by acyclovir, treatment group Ⅱ in the treatment group Ⅰ plus Tanreqing treatment. Results The total effective rates of the control group, treatment group Ⅰ and treatment group Ⅱ were 94%, 92% and 98% respectively. There was significant difference between the treatment group Ⅱ and the control group (p <0.01) There was significant difference (p <0.01), while there was no difference between the treatment group Ⅰ and the control group (p> 0.05). Conclusion Aciclovir combined with Tanreqing treatment of respiratory syncytial virus pneumonia in infants with significant effect.