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[目的]观察补肾壮骨汤联合西药治疗原发性骨质疏松症疗效。[方法]使用随机平行对照方法,将56例住院及门诊患者按抛硬币法随机分为两组。对照组28例阿法骨化醇胶囊,首次0.25μg/次,1次/d;逐渐增加剂量直至2μg/d。钙尔奇D,0.75g/次,1次/d。治疗组28例补肾壮骨汤(当归、熟地各10g,黄芪30g,茯苓22g,白术13g,白芍15g,炙甘草、陈皮各10g,山药12g,薏苡仁15g,牛膝12g,补骨脂、巴戟天、龟板各10g);1剂/d,水煎200mL,3次/d。西药治疗同对照组。两组均连续治疗30d为1疗程。观测临床症状、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组显效18例,有效6例,无效4例,总有效率85.70%。对照组显效10例,有效7例,无效11例,总有效率60.71%。治疗组疗效优于对照组(P<0.05)。[结论]补肾壮骨汤联合西药治疗原发性骨质疏松症效果显著,值得推广。
[Objective] To observe the therapeutic effect of Bushen Zhuanggu Decoction combined with Western medicine on primary osteoporosis. [Methods] Using randomized parallel control method, 56 inpatients and outpatients were randomly divided into two groups according to the coin tossing method. The control group, 28 cases of alfacalcidol capsules, the first 0.25μg / times, 1 / d; gradually increase the dose until 2μg / d. Calcium odd D, 0.75g / time, 1 time / d. The treatment group, 28 cases of Bushen Zhuanggu Tang (Angelica, Rehmannia each 10g, Astragalus 30g, Poria 22g, Atractylodes 13g, white peony root 15g, Zhigancao, dried tangerine peel 10g, yam 12g, Coix 15g, Achyranthes 12g, Morinda, turtle shell each 10g); 1 / d, decoction 200mL, 3 times / d. Western medicine treatment with the control group. Continuous treatment of both groups 30d for a course of treatment. Observed clinical symptoms, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Results] The treatment group markedly effective in 18 cases, effective in 6 cases, 4 cases, the total effective rate was 85.70%. Control group markedly effective in 10 cases, effective in 7 cases, ineffective in 11 cases, the total effective rate was 60.71%. The treatment group was better than the control group (P <0.05). [Conclusion] Bushen Zhuanggu Decoction combined with Western medicine has significant effect on primary osteoporosis and is worth popularizing.