穿孔病（又称疖疮病、空穴病），为鳖的主要病害之一。由病鳖体内分离出三株细菌，其中二株经感染健康鳖得到与病鳖相同症状。经过病原学检验和毒力感染试验，证明了引起该病的病原菌为气单胞菌（Ａｅｒｏｍｏｎａｓｓｐ）和产碱菌（Ａｌｃａｌｉｇｅｍｅｓｓｐ）。本文介绍了该病的流行病学、病原菌分离、鉴定、毒力感染试验及药物敏感性试验等方面的研究。 Perforating disease (also known as scabies disease, hole disease), one of the main diseases for turtle. Three strains of bacteria were isolated from diseased turtles, of which two were infected with healthy turtles to obtain the same symptoms as diseased turtles. After pathogenicity test and virulent infection test, the pathogen causing the disease was proved to be Aeromonasp and Alcaligemessp. This article describes the epidemiology of the disease, pathogenic bacteria isolation, identification, virulence tests and drug susceptibility testing and other aspects of the study.