论文部分内容阅读
目的:探讨单纯病毒性角膜炎患者应用中西医结合治疗疗效及其安全性,为临床治疗提供一定的参考价值。方法:本组108例患者根据随机数字表法随机分为观察组(n=54)和对照组(n=54)。对照组采用西药治疗,观察组在对照组基础上结合中医方剂治疗。两组患者疗程均为4周。疗程结束后对比两组治疗疗效,治疗后视力变化、角膜云翳程度、总治疗时间,治疗过程中不良反应发生情况及治疗后随访6个月复发情况。结果:观察组治疗4周后总有效率(88.89%)显著高于对照组(74.07%),且具有统计学差异(P<0.05);观察组治疗后视力明显高于对照组,角膜云翳程度显著低于对照组,总治疗时间显著短于对照组,且均具有统计学差异(P<0.05);治疗过程中两组患者均未发生明显不良反应;随访6个月观察组复发率显著低于对照组,且具有统计学差异(P<0.05)。结论:单纯性病毒性角膜炎患者应用中西医结合治疗疗效显著,无明显反应,复发率低,临床应用安全可靠,具有重要研究价值。
Objective: To investigate the efficacy and safety of traditional Chinese medicine and western medicine in patients with simple viral keratitis and provide some reference value for clinical treatment. Methods: A total of 108 patients in this group were randomly divided into observation group (n = 54) and control group (n = 54) according to the random number table method. The control group was treated with western medicine, while the observation group was treated with traditional Chinese medicine based on the control group. Two groups of patients were treated for 4 weeks. After the end of treatment, the curative effect of the two groups were compared, the change of visual acuity after treatment, the degree of corneal nebula, the total treatment time, the incidence of adverse reactions in the course of treatment and the recurrence after 6 months of follow-up. Results: After 4 weeks of treatment, the total effective rate (88.89%) in the observation group was significantly higher than that in the control group (74.07%) (P <0.05); the visual acuity of the observation group was significantly higher than that of the control group Significantly lower than the control group, the total treatment time was significantly shorter than the control group, and both were statistically significant (P <0.05); during treatment no significant adverse reactions occurred in both groups; the recurrence rate was significantly lower in the observation group 6 months follow-up In the control group, with statistical significance (P <0.05). Conclusion: The treatment of simple virus keratitis in patients with Integrative Medicine significant effect, no significant response, low recurrence rate, safe and reliable clinical application, has important research value.