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自Linus Pauling发表他所著的“维生素与感冒”一书以来,引起了人们对维生素C相当大的关注。尤其在美国,已成为所有维生素中消费量最大的一种。为此,需要生产含量高、片形小的维生素片。但由于维生素C可压性很差,在受潮情况下又易于变色。因此要制得具备满意的硬度和稳定性的维生素C片是有困难的。维生素C的可压性差归咎于颗粒间的粘结力差。为此,常需与粘结剂一起造粒以改善其可压性。因为维生素C的晶体易碎,以致在压制过程中易破坏,由于配伍问题,不能使用淀粉浆之外的粘结剂以及维生素C在
Since Linus Pauling published his book “Vitamins and Colds,” a great deal of attention has been drawn to Vitamin C. Especially in the United States, it has become the largest consumer of all vitamins. To this end, the need to produce high content, small pieces of vitamin tablets. However, due to poor compressibility of vitamin C, in the case of moisture and easy to change color. Therefore, to obtain a satisfactory hardness and stability of vitamin C tablets is difficult. The poor compressibility of vitamin C is attributed to the poor adhesion between the particles. For this reason, it is often necessary to pelletize with a binder to improve its compressibility. Because the crystals of vitamin C are fragile and easily broken during the pressing process, sticking agents other than starch paste and vitamin C can not be used due to compatibility problems