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目的了解密云县中医院2006年抗菌药物ADR监测情况,进一步加强临床抗菌药物使用的安全、合理性,更好地促进合理用药。方法对密云县中医院19例抗菌药物引发的ADR进行回顾性调查分析。结果抗菌药物ADR发生与患者一般情况、药物种类、剂型等因素相关。结论抗菌药物ADR发生例数中,喹诺酮类药物占总例数的47.37%,其中左氧氟沙星注射液占总例数的26.32%,注射用加替沙星冻干粉针占15.79%,提示医务人员在临床应用此类抗菌药时应详细询问患者既往过敏史,并密切观察患者用药期间有无不适症状,以减少ADR的发生。
Objective To understand the monitoring status of antimicrobial ADR in Miyun County Hospital of Traditional Chinese Medicine in 2006 so as to further enhance the safety and rationality of clinical antimicrobial agents and promote the rational use of drugs. Methods Retrospective analysis of 19 cases of antimicrobial drug-induced ADR in Miyun County Hospital of Traditional Chinese Medicine. Results The occurrence of antimicrobial agents ADR and the general situation of patients, drug types, dosage forms and other factors. Conclusion The number of antibiotics ADR cases accounted for 47.37% of the total cases, of which levofloxacin injection accounted for 26.32% of the total number of cases, injection of gatifloxacin freeze-dried powder accounted for 15.79%, suggesting that medical staff at Clinical application of such antimicrobial agents should be asked in detail about the history of patients with past allergies, and close observation of patients with or without symptoms during treatment, in order to reduce the incidence of ADR.