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溶栓疗法治疗急性心肌梗塞(AMI)能缩小梗塞范围,保存心室功能,提高存活率;但治疗成功的病例中,再次梗塞和心脏猝死危险仍然较大。显然,溶栓疗法还需配合一些辅助治疗,如β阻滞剂、镁、硝酸酯、钙拮抗剂、ACE抑制剂等。β阻滞剂据证明,在AMI早期(症状开始12小时内),静注β阻滞剂可缩小梗塞范围,减少复杂的室性心律失常,使病死率下降13％;这一效益在AMI后最初2日内最明显。β阻滞剂还能使非致死性再次梗塞和心脏骤停人数分别减少19％和16％。
Thrombolytic therapy for acute myocardial infarction (AMI) can reduce the infarct size, preservation of ventricular function and improve survival; However, the successful treatment of cases, the risk of re-infarction and sudden cardiac death is still large. Obviously, thrombolytic therapy need to be accompanied by some adjuvant therapy, such as beta blockers, magnesium, nitrates, calcium antagonists, ACE inhibitors. Beta Blockers It has been demonstrated that intravenous beta blockers reduce infarct size and reduce complex ventricular arrhythmias, leading to a 13% reduction in mortality in the early AMI (within 12 hours of symptom onset); this benefit is demonstrated after AMI The first 2 days the most obvious. Beta blockers also reduced the number of non-fatal recurrent infarcts and cardiac arrest by 19% and 16%, respectively.