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目的:观察热毒宁注射液联合阿昔洛韦注射液联合治疗小儿水痘的临床疗效。方法:将60例水痘患儿随机分成治疗组和对照组,每组各30例,治疗组给予热毒宁注射液0.6~0.8m l/k g,每天一次,同时给与阿昔洛韦注射液(10m l·k g-1),每天一次,静脉滴注,连续5~7天,对照组仅给予阿昔洛韦注射液(10m l·k g-1),每天一次,连续5~7天,治疗后观察两组疗效,包括患儿发热持续时间、皮疹结痂、消退时间及不良反应。结果:治疗组有效率为100%,对照组有效率为90%,两组之间的差异有统计学意义(P<0.05)。两组均未发生明显不良反应。结论:热毒宁联合阿昔洛韦注射液治疗小儿水痘优于单用阿昔洛韦注射液,且安全性高,不良反应少。“,”Objective To observe the clinical effect of Reduning injection combined with acyclovir in children with varicella.Methods Children were divided into treatment group and control group, treatment group given Reduning injection, also given acyclovir injection, while the control group was only treated with acyclovir injection observed the curative effect of the two groups.Results The total effective rate of treatment group 100% was higher than that of control group 90%,the difference was statistically significant(P<0.05).The fever time and rash subsided time of treatment group were shorter than those of control group,the difference were statistically significant (P<0.05).NO significantadverse reactions occurred .Conclusion Reduning combined with Aciclovir Injection treatment of high safety, less adverse reaction.