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报告31例冠心病患者和23例正常对照者血浆TxB_2、6-酮-PGF_(1α)及Von Willebrand因子测定的结果。发现TxB_2、VWF浓度及TxB_2/6-酮-PGF_(1α)比值均明显高于对照组,6-酮-PGF_(1α)值有降低趋势,但与对照组比较无统计学意义。结果提示冠心病患者的血小板易于活化并有血管内皮细胞的损伤。
The results of plasma TxB 2, 6-keto-PGF_ (1α) and Von Willebrand factor assays in 31 patients with coronary heart disease and 23 normal controls were reported. The concentrations of TxB_2, VWF and TxB_2 / 6-keto-PGF_ (1α) were found to be significantly higher than those of the control group. The values of 6-keto-PGF_ (1α) tended to decrease, but not statistically significant compared with the control group. The results suggest that platelets in patients with coronary heart disease tend to be activated and vascular endothelial cell damage.