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目的探讨峰龄胶囊对恶性肿瘤患者化疗期间Ｔ淋巴细胞亚群功能的影响。方法应用流式细胞术对４０例恶性肿瘤常规化疗患者治疗前后Ｔ淋巴细胞亚群进行动态观察８周。结果治疗前治疗组与对照组比较，Ｔ淋巴细胞亚群各参数差异无显著性（Ｐ＞０．０５）；治疗后治疗组与对照组比较，治疗组ＣＤ＋３、ＣＤ＋４、ＣＤ＋４／ＣＤ＋８显著升高，ＣＤ＋８显著下降（Ｐ＜０．０１，Ｐ＜０．００１）；两组治疗前后自身对照：对照组ＣＤ＋３、ＣＤ＋８轻度升高，但无统计学意义（Ｐ＞０．０５）；治疗组ＣＤ＋３、ＣＤ＋４、ＣＤ＋４／ＣＤ＋８显著升高，ＣＤ＋６显著下降，均有统计学意义（Ｐ＜０．００１）。结论峰龄能显著提高恶性肿瘤患者化疗期间的Ｔ淋巴细胞亚群功能，改善免疫机能，抵御化疗药物对机体免疫功能的抑制作用。
Objective To investigate the effect of Fengling Capsule on the function of T lymphocyte subsets in patients with malignant tumor during chemotherapy. Methods Flow cytometry was used to observe the T-lymphocyte subsets before and after treatment in 40 patients with conventional chemotherapy. Results There was no significant difference in T-lymphocyte subsets before treatment between treatment group and control group (P>0.05). After treatment, there was a significant increase in CD+3, CD+4, and CD+4/CD+8 in treatment group compared with control group. CD+8 decreased significantly (P<0.01, P<0.001); self-control before and after treatment in both groups: CD+3 and CD+8 in the control group increased slightly, but there was no statistical significance (P>0.05); CD+3, CD+4, CD+4/CD+8 were significantly increased, and CD+6 was significantly decreased, both statistically significant (P<0.001). Conclusion Fengling can significantly improve the function of T-lymphocyte subsets during chemotherapy in patients with malignant tumors, improve immune function, and resist the inhibitory effect of chemotherapy drugs on immune function.