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通过对阻塞性黄疸大鼠腹腔巨噬细胞IL-1、脾脏淋巴细胞IL-2生成能力测定,同时观察人参皂甙对阻塞性黄疸大鼠其它免疫功能的影响。结果发现结扎大鼠胆管后腹腔巨噬细胞IL-1及脾脏淋巴细胞IL-2生成能力均明显下降。应用人参皂甙治疗结扎胆管的大鼠,可明显改善其腹腔巨噬细胞IL-1及脾脏淋巴细胞IL-2的生成能力。提示人参皂甙可改善阻塞性黄疸大鼠的免疫功能。
The effects of ginsenosides on other immunological functions in obstructive jaundice rats were observed by measuring the production of IL-1 in peritoneal macrophages and IL-2 in spleen of obstructive jaundice rats. The results showed that IL-1 production by peritoneal macrophages and IL-2 production by splenic lymphocytes were significantly decreased after ligation of rat bile duct. Application of ginsenoside in the treatment of ligation of the bile duct can significantly improve its peritoneal macrophages IL-1 and spleen lymphocytes IL-2 production capacity. Tip ginsenosides can improve the immune function of obstructive jaundice rats.