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目的:观察连续性血液净化(CBP)在重症烧伤患者救治中的作用。方法:7例大面积重度烧伤患者,合并全身炎症反应综合征(SIRS)/脓毒症,和(或)多脏器功能不全综合征(MODS),在接诊24h内实施CBP治疗。记录患者生命体征、血常规、血生化、肝功能、肾损伤指标,炎症指标、28d及6个月死亡率。结果:7例患者平均烧伤总面积达91.1%,28d死亡率28.6%(2/7),6个月死亡率42.9%(3/7)。患者血压、体温、炎症指标、血糖、血钠、尿量等与预后密切相关的指标相对稳定。结论:重度烧伤患者及早实施CBP治疗能减轻SIRS/脓毒症、改善内环境、保护重要脏器功能和改善预后。
Objective: To observe the role of continuous blood purification (CBP) in the treatment of severe burn patients. Methods: Seven patients with extensive severe burn with systemic inflammatory response syndrome (SIRS) / sepsis and / or multiple organ dysfunction syndrome (MODS) were treated with CBP within 24 hours of admissions. The patient’s vital signs, blood routine, blood biochemistry, liver function, renal injury index, inflammation index, 28d and 6 months mortality were recorded. Results: The average burn area was 91.1% in 7 patients, 28.6% (2/7) in 28 days and 42.9% (3/7) in 6 months. Patients with blood pressure, body temperature, inflammation indicators, blood glucose, serum sodium, urine output and other prognostic indicators are relatively stable. Conclusions: Early treatment with CBP in severe burn patients can reduce SIRS / sepsis, improve the internal environment, protect vital organs and improve prognosis.