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目的:采用多巴酚丁胺负荷超声心动图评价急性心肌梗死后梗死区域心肌的存活性。方法:36例急性心肌梗死病人进入本研究,分别采用5μgkg-1/min和10μgkg-1/min的多巴酚丁胺静脉滴注,体表超声心动图观察梗死区域心肌收缩心室壁运动和厚度的变化,以识别有无存活心肌。结果:对36例病人分析了576段心肌,基础状态时94段心肌运动消失;119段心肌运动减低;363段心肌为正常心肌。静脉滴注5μgkg-1/min多巴酚丁胺后,运动消失的94段心肌中,30段心肌心室壁运动及收缩心室壁增厚率得到了改善,其中23段心肌变为运动减弱心肌,7段心肌变为正常心肌,将多巴酚丁胺增量至10μgkg-1/min后,由第1次剂量无反应的运动消失的64段心肌中,有5段心肌心室壁运动和收缩心室壁增厚率得到改善。结论:采用多巴酚丁胺负荷超声心动图对急性心肌梗死后存活心肌的识别是安全的,而且具有十分重要的临床意义。
OBJECTIVE: To evaluate the viability of myocardial infarction area after dobutamine stress echocardiography. Methods: Thirty-six patients with acute myocardial infarction were enrolled in this study. Intravenous echocardiography was used to observe the contractile ventricular wall motion and thickness in the infarcted area with doxorubicin (5μgkg-1 / min and 10μgkg-1 / Changes to identify whether there is viable myocardium. Results: A total of 576 segments of myocardium were analyzed in 36 patients. During the basal state, 94 segments of myocardial motion disappeared. 119 segments of myocardium decreased. 363 segments of myocardium were normal myocardium. After intravenous instillation of 5μg kg-1 / min dobutamine, the myocardial segments of 94 segments disappeared in 30 segments and the thickened ventricular wall was improved. Among them, the 23 segments of myocardium became myocardial weakening, Seven segments of the myocardium were changed to normal myocardium. After the dobutamine was increased to 10 μgkg-1 / min, there were 5 segments of myocardial ventricular wall motion and contracting ventricle in the 64 segments of myocardium that disappeared from the first dose of non-responsive exercise Wall thickening rate is improved. CONCLUSION: The use of dobutamine stress echocardiography for the identification of viable myocardium after acute myocardial infarction is safe and has very important clinical implications.