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在心力衰竭(HF)患者中心肾综合征(CRS)非常常见,其与预后不良有关。目前,CRS的发病机制尚不清楚。由于肾功能恶化和利尿剂抵抗,CRS的治疗更加困难。包括B型利钠肽、超滤、持续的呋塞米输注、加压素受体拮抗剂和腺苷受体拮抗剂等的综合治疗可能效果较好。CRS的发病机制和治疗还需要进一步的研究。
Central-renal syndrome (CRS) is very common in patients with heart failure (HF) and is associated with poor prognosis. At present, the pathogenesis of CRS is not clear. Treatment of CRS is more difficult due to deteriorating renal function and diuretic resistance. A combination of B-type natriuretic peptide, ultrafiltration, sustained furosemide infusion, vasopressin receptor antagonist and adenosine receptor antagonist may work well. The pathogenesis and treatment of CRS need further study.