近10年来,人们已认识到细胞因子(cy-tokines,CKs)是启动和调控免疫细胞之间复杂交往的介质。其中不少因子还能调节免疫细胞与内皮细胞、纤维母细胞、上皮细胞等多种细胞之间的相互作用。因而在介导炎症反应、抗感染免疫、自身免疫、变态反应、肿瘤、移植和造血等方面起着重要作用。同时也对与这些病理变化相关疾病的治疗提示了新的策略。已 For nearly 10 years, it has been recognized that cy-tokines (CKs) are mediators that initiate and regulate complex interactions between immune cells. Many of these factors can also regulate the interaction between immune cells and endothelial cells, fibroblasts, epithelial cells and other cells. Thus playing an important role in mediating inflammatory response, anti-infective immunity, autoimmunity, allergy, cancer, transplantation and hematopoiesis. It also suggests new strategies for the treatment of diseases associated with these pathological changes. Already