肌张力障碍是由主动肌和拮抗肌的不协调收缩或过度收缩引起的以异常姿势和动作为特征的常见运动障碍性疾病,发病机制复杂,临床表现多样。文章着重论述原发性肌张力障碍、肌张力障碍叠加综合征和遗传性肌张力障碍的致病基因、临床特征及遗传学研究进展。 Dystonia is a common movement disorder characterized by abnormal posture and movements caused by uncoordinated or over-contracted aortic muscle and antagonist muscle. The pathogenesis is complex and has various clinical manifestations. This article focuses on the primary dystonia, dystonia syndrome and genetic dystonia disease genes, clinical features and genetic research.