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目的探讨血清胆碱酯酶(CHE)活性测定在结肠癌诊断中的价值。方法采用速率法检测56例经肠镜活检或外科手术病理证实的结肠癌患者(其中男性30例,女性26例)血清中胆碱酯酶的含量,并与40例正常对照者比较,对结果进行分析。结果30例男性结肠癌患者血清CHE含量为4015.52±818.87U/L,正常组为7877.90±1769.38U/L,两者差异显著(P<0.01);26例女性患者血清CHE含量为3879.03±715.34U/L,正常组为6384.90±1315.37U/L,两者差异显著(P<0.01)。结论血清CHE活性测定可作为诊断结肠癌的标志物,对结肠癌患者的筛查和诊断具有重要的临床意义。
Objective To investigate the value of serum cholinesterase (CHE) activity in the diagnosis of colon cancer. Methods The rate of cholinesterase in serum of 56 patients with colon cancer (30 males and 26 females) confirmed by colon biopsy or surgical pathology was detected by the rate method and compared with 40 normal controls. Analyze. Results The serum levels of CHE were 4015.52 ± 818.87U / L and 7877.90 ± 1769.38U / L in the 30 male patients with colorectal cancer (P <0.01). The serum CHE levels in the 26 women were 3879.03 ± 715.34U / L, the normal group was 6384.90 ± 1315.37U / L, the difference was significant (P <0.01). Conclusion Serum CHE activity can be used as a marker for the diagnosis of colon cancer, screening and diagnosis of patients with colon cancer has important clinical significance.