论文部分内容阅读
目的探讨C-反应蛋白(CRP)诊断胎膜早破急性绒毛膜羊膜炎的临床价值。方法收集200例胎膜早破病例血清测定CRP水平及白细胞计数。每例组织绒毛膜羊膜炎通过产后胎盘病理证实,按病理结果分为绒毛膜羊膜炎组(n=35)及非绒毛膜羊膜炎组(n=165)。结果 (1)绒毛膜羊膜炎组和非绒毛膜羊膜炎组比较,CRP有统计学意义(P<0.01),白细胞计数的差异无统计学意义,WBC、CRP对预测绒毛膜羊膜炎的灵敏度和特异度分别为59.86%、85.73%和48.35%、76.08%。结论胎膜早破孕妇母血中的CRP较WBC对诊断绒毛膜羊膜炎灵敏,胎膜早破时测定CRP对预测宫内感染有很好的临床价值。
Objective To investigate the clinical value of C-reactive protein (CRP) in the diagnosis of acute chorioamnionitis with premature rupture of membranes. Methods Serum samples of 200 cases of premature rupture of membranes were collected to measure CRP level and white blood cell count. Chorioamnionitis was confirmed by placental pathology in each case and was divided into chorioamnionitis group (n = 35) and non-chorioamnionitis group (n = 165) according to pathological results. Results (1) CRP was significantly higher in chorioamnionitis group than in non-chorioamnionitis group (P <0.01), while there was no significant difference in white blood cell count. The sensitivity of WBC and CRP in predicting chorioamnionitis and The specificity was 59.86%, 85.73% and 48.35%, 76.08% respectively. Conclusion The CRP in premature rupture of membranes of pregnant women with premature rupture of membranes is more sensitive than that of WBC in the diagnosis of chorioamnionitis. The determination of CRP during premature rupture of fetal membranes has good clinical value in predicting intrauterine infection.