干细胞移植修复缺血性心肌损伤已取得很好的收益,可减小梗死面积,提高左心功能和心脏灌注。目前输注的方法主要有冠状动脉内注射及心肌注射等。但仍存在一些问题:如移植干细胞存活率低、衰老并丧失多向分化能力等。如何优化干细胞的类型、移植方式及输注时机,是将来的研究方向。 Stem cell transplantation to repair ischemic myocardial injury has made good gains, can reduce the infarct size, improve left ventricular function and cardiac perfusion. Currently the main method of infusion of intracoronary injection and myocardial injection. However, there are still some problems: such as low survival rate of transplanted stem cells, aging and loss of multidirectional differentiation ability. How to optimize the type of stem cells, transplantation and infusion timing, is the future direction of the study.