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1975年7月~1991年12月收治住院成人喉乳头状瘤42例,单发35例,多发7例。平均年龄52.4岁,均获随访。42例中11例恶变(26.2%)。19例伴上皮非典型增生,占45.2%。成人单发喉乳头状瘤手术治疗应留有一定的安全缘,而多发性的应用电烧,术后辅助干扰素治疗取得了满意的效果。本文并对其病因、恶变、恶变与上皮非典型增生的关系以及治疗复发问题进行讨论。
From July 1975 to December 1991, 42 cases of laryngeal papilloma were admitted to hospital, 35 cases were single and 7 cases were multiple. The average age was 52.4 years and were followed up. Eleven of the 42 patients were malignant (26.2%). 19 cases with epithelial atypical hyperplasia, accounting for 45.2%. Surgical treatment of single laryngeal papilloma should have a certain margin of safety, and multiple applications of electrocautery, postoperative adjuvant interferon therapy has achieved satisfactory results. This article and its etiology, malignant transformation, malignant transformation and epithelial dysplasia and the relationship between the treatment of recurrence are discussed.