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目的 :观察 3组癌细胞系中TM4SF蛋白CD37、CD5 3的表达。方法 :利用Northernblot杂交 ,观察CD37、CD5 3mRNA在人前列腺癌细胞、肺癌细胞和人黑色素瘤细胞 3组 8种细胞系中的表达。结果和结论 :TM4SF蛋白CD37、CD5 3在前列腺癌细胞、肺癌细胞以及黑色素瘤细胞系中均不表达。
Objective: To observe the expression of TM4SF protein CD37 and CD5 3 in three groups of cancer cell lines. Methods : Northern blot hybridization was used to observe the expression of CD37 and CD5 3 mRNA in human prostate cancer cells, lung cancer cells and human melanoma cells. Results and conclusions: The TM4SF proteins CD37 and CD5 3 were not expressed in prostate cancer cells, lung cancer cells and melanoma cell lines.