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活血化瘀冠心Ⅱ号方对冠心病及闭塞性脑血管病有较好疗效。最近从整体、细胞及分子水平进一步证实冠心Ⅱ号方及其有效成分具有调整心肌血流动力学、保护缺血心肌、调节体外培养心肌细胞搏动频率、保护心肌细胞缺氧性损伤等作用。本文报告该方对小鼠心肌营养血流量的影响。 健康小鼠七十四只,体重18～20g,按随机原则分为给药组及对照组配对实验。冠心Ⅱ号注射液由本室制备。~(86)RbCl由中国科学院原子能所提供,溶解在0.9％NS中,比放射性为0.8μCi/mol。
Huoxuehuayuang heart on the 2nd party on coronary heart disease and occlusive cerebrovascular disease have a good effect. Recently, it has been further confirmed from the whole body, cells and molecular level that Guanxin Ⅱ Prescription and its active ingredients can regulate myocardial hemodynamics, protect ischemic myocardium, regulate cardiomyocyte pulsatility frequency in vitro and protect myocardial cells from hypoxic injury. This article reports the effect of this side on cardiac nourishing blood flow in mice. Seventy-four healthy mice, weighing 18 ~ 20g, were randomly divided into experimental group and control group. Coronary Heart II injection prepared by the room. ~ (86) RbCl was provided by Atomic Energy Institute of Chinese Academy of Sciences and dissolved in 0.9% NS with specific radioactivity of 0.8 μCi / mol.