在Grares＇病(巴塞杜氏病)伴有的眼球突出及眼球运动障碍时,称为Grares眼症。早在17世纪前半叶Parry.Graves Basedaw等之前10世纪时拜占庭律书中即有过记载。但是Graves眼症与甲状腺异常之间在关系至今仍是不解之迷。近年来对本病的主要症状——甲状腺机能亢进的研究表明本病与自身免疫机制有关。并观察到此病在异常甲状腺刺激素(TSH)的甲状腺受体中有抗体。但是Graves眼症与TSH受体抗体的直接关系尚不明确。 Grares’ disease (Pertussis disease) associated with eyeballs and eye movement disorders, known as Grares eye disease. As early as in the first half of the seventeenth Century Parry.Graves Basedaw, etc. before the 10th century Byzantine law books that have been recorded. However, the relationship between Graves ophthalmopathy and thyroid abnormality is still puzzled. In recent years, the main symptoms of this disease - hyperthyroidism studies have shown that the disease and autoimmune mechanism. And the disease was observed in abnormal thyroid stimulating hormone (TSH) thyroid receptors have antibodies. However, the direct relationship between Graves ophthalmia and TSH receptor antibodies is unclear.