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目的探讨参芪扶正注射液减轻化疗不良反应的临床效果。方法选取安阳市肿瘤医院2006年1月至2008年12月进行诊疗的恶性肿瘤患者98例,以数字表法将患者随机平均分为两组,分别进行常规放化疗与参芪扶正注射液联合治疗。结果两组患者治疗前的淋巴细胞亚群比较差异无统计学意义(P>0.05),治疗后观察组的淋巴细胞亚群无明显变化(P>0.05),对照组治疗后淋巴细胞亚群显著减少(P<0.05)。观察组患者免疫功能保护效果明显优于对照组。观察组总有效率优于对照组,生活质量显著提高(P<0.05)。观察组放疗化疗不良反应较对照组显著减少(P<0.01)。结论参芪扶正注射液有效改善患者免疫系统的损伤,有效提高患者的生存质量,减少了不良反应的发生率,在肿瘤放疗与化疗的治疗中具有良好的效果。
Objective To investigate the clinical effects of Shenqi Fuzheng injection on alleviating adverse reactions of chemotherapy. Methods 98 patients with malignant tumors diagnosed and treated in Anyang Tumor Hospital from January 2006 to December 2008 were randomly divided into two groups according to the digital meter method. The patients were treated with conventional radiotherapy combined with Shenqi Fuzheng injection . Results There was no significant difference in lymphocyte subsets between the two groups before treatment (P> 0.05). There was no significant change in the lymphocyte subsets in the observation group after treatment (P> 0.05), while the lymphocyte subsets in the control group were significant Decrease (P <0.05). The immune function in the observation group was significantly better than that in the control group. The total effective rate in the observation group was better than that in the control group, and the quality of life was significantly improved (P <0.05). Adverse reactions of radiotherapy and chemotherapy in observation group were significantly lower than those in control group (P <0.01). Conclusion Shenqi Fuzheng injection can effectively improve the immune system in patients with injuries, effectively improve the quality of life of patients and reduce the incidence of adverse reactions in the treatment of tumor radiotherapy and chemotherapy has a good effect.