论文部分内容阅读
目的:分析不同类型的吉兰-巴雷综合征(GBS)患者的临床表现及预后。方法:以电生理方法将63例患者分为脱髓鞘型、轴索型和未分类型。比较脱髓鞘型和轴索型患者的临床表现、疾病高峰期及出院时的神经功能残疾评分。结果:轴索型和脱髓鞘型患者疾病高峰期神经功能残疾评分分别为(4.0±1.05)分和(2.8±0.98)分,出院时分别为(2.6±1.84)分和(1.3±0.75)分,两组间评分差异有统计学意义(均P<0.01)。轴索型患者有较高比例的前趋期腹泻和呼吸肌麻痹症状发生,但感觉异常少见。结论:轴索型GBS患者易有前躯期腹泻和呼吸肌麻痹的临床表现,其病情重、预后差。
Objective: To analyze the clinical manifestations and prognosis of patients with different types of Guillain-Barré Syndrome (GBS). Methods: 63 patients were divided into demyelinating, axonal and unsorted type by electrophysiology. To compare the clinical features of demyelinating and axonal patients, the peak of the disease and neurological disability score at discharge. Results: Neurological disability scores at the peak of disease were (4.0 ± 1.05) and (2.8 ± 0.98) points respectively in patients with axonal and demyelinating diseases and were (2.6 ± 1.84) and (1.3 ± 0.75) points at discharge respectively There was significant difference between the two groups (all P <0.01). Axial patients have a higher proportion of pro-phase diarrhea and respiratory muscle paralysis, but the sensory abnormalities are rare. Conclusions: Axolous GBS patients are predisposed to clinical manifestations of anterior segment diarrhea and respiratory muscle paralysis. Their severity and prognosis are poor.