自1850年Arnn氏发表了有关进行性肌营养不良的文献以来,多数人认为这是一种骨骼肌原发性退化性疾病,对其病因未完全清楚。在分类方面,一百多年来,各家凭其临床覌察,列出了种种分类名称,可是直到現在,还沒有一种被公认为較理想的分类。家族性与遺传傾向可以說是本病的特征之一,但无家族性者为数亦頗不少,如Tyler,PerkoffWalton,Dubowitz等氏,基于遺传学摩尔根学派的論点,认为所謂Duchenne型常为隐性性联遺传而有突变,故主要为男性患者,至于所謂面肩胛肱型則为显性遺传,男女性患者都有。本病的治疗效果远不能令人滿意。 Since Arnn’s 1850 publication of a literature on progressive muscular dystrophy, most people consider it a primary degenerative disease of skeletal muscle, the cause of which is not fully understood. In terms of classification, for more than one hundred years, various clinical names have been listed by various clinics. However, until now, no classification has been accepted as a more satisfactory one. Familial and genetic predisposition can be said to be one of the characteristics of the disease, but there are quite a few non-familial ones, such as Tyler, Perkoff Walton, Dubowitz et al. Based on the argument of Genetics School of Morgan that the so-called Duchenne type Often hidden genetic mutations have mutations, it is mainly for male patients, as the so-called surface scapular brachial type is dominant genetic, male and female patients have. The treatment of this disease is far from satisfactory.