论文部分内容阅读
用化学药物治疗肿瘤的方法称为肿瘤化疗,它与手术、放疗为目前肿瘤治疗的3个主要方法。肿瘤化疗对于消灭微小肿瘤转移灶和手术切除后的残留肿瘤细胞有手术与放疗无法达到的优势,但肿瘤化疗中仍有许多问题需要解决:①肿瘤病人个体间对化疗药物敏感性差异大;②肿瘤对化疗药物有耐药性;③化疗药物对许多类型的肿瘤特别是实体瘤的有效率不高;④化疗药物的选择性差,毒性大,杀伤癌细胞的同时也杀伤正常细胞,给病人机体造成较大的损害。
Chemotherapy for the treatment of cancer is called tumor chemotherapy, and surgery and radiotherapy are the three main methods of cancer treatment. Chemotherapy of tumor has the advantages that can not be achieved by surgery and radiotherapy in eradicating tiny tumor metastasis and residual tumor cells after surgical resection. However, there are still many problems in tumor chemotherapy that need to be solved: (1) there is a big difference in chemosensitivity among tumor patients; The tumor is resistant to chemotherapeutic drugs; ③ the chemotherapeutic drugs are not efficient for many types of tumors, especially solid tumors; ④ the selectivity of chemotherapeutic drugs is poor, the toxicity is high, and the cancerous cells kill the normal cells as well as the body Cause greater damage.