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目的 :分析不同手术时机治疗急性重症胆管炎的疗效差异,为早期手术干预此类患者提供临床依据。方法 :选择2014年12月~2015年12月在我院接诊的80例急性重症胆管炎患者资料进行研究,根据手术治疗时机的不同分为观察组与对照组,观察组40例患者,均为入院8h内行手术治疗,对照组40例患者,在入院8h后进行手术,比较两组患者一般临床资料、术后24h血总胆红素、直接胆红素、胆汁引流量、APACHE-Ⅱ评分以及预后情况。结果 :1察组术后24h胆汁引流量、血总胆红素、直接胆红素、APACHE-Ⅱ评分与对照组相比,差异有统计学意义;2观察组并发症发生率、发生功能能障碍器官个数与住院天数明显低于对照组,差异有统计学意义;两组患者病死率差异无统计学意义。结论 :早期施行手术有助于改善急性重症胆管炎的预后,提高临床治疗效果。
OBJECTIVE: To analyze the difference in the curative effect of different operation timing in the treatment of acute cholangitis of severe acute cholangitis, and provide the clinical evidence for such patients in early surgical intervention. Methods: 80 patients admitted to our hospital from December 2014 to December 2015 were selected to study the data of patients with acute cholangitis. According to the timing of the operation, the patients were divided into observation group and control group. 40 patients in the observation group Eight hours after admission, 40 patients in the control group underwent surgery. The clinical data of the two groups were compared. The levels of total bilirubin, direct bilirubin, bile drainage, APACHE-Ⅱ score As well as the prognosis. Results: The biliary drainage, total bilirubin, direct bilirubin, and APACHE-Ⅱ scores in 1 observation group after operation were significantly different from those in control group. 2 The complication incidence rate, Obstructive organs and hospitalization days were significantly lower than the control group, the difference was statistically significant; two groups of patients with no significant difference in mortality. Conclusion: Early operation will help to improve the prognosis of acute cholangitis and improve the effect of clinical treatment.