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In order to avoid the therapeutic reaction and the side effects oforal administration of Diethylcarbamazine(DEC)the authors first reportedthe transepidermal application of 10% DEC cream for treating lymphaticbancroftian filariasis in human.The study was carried out among 135microfilariemia patients who were divided into three groups in Xiping county,Henan province,China.The result shows a marked therapeutic efficacy.Themicrofilaria counts decrease and become negative at the rate of 89.5% in the8th month and 93.5% in the 12th month after the treatment.Compared withthe oral administration this method is more effective and has no side effectsduring the therapy.
In order to avoid the therapeutic reaction and the side effects oforal administration of Diethylcarbamazine(DEC)the authors first reportedthe transepidermal application of 10% DEC cream for treating lymphaticbancroftian filariasis in human.The study was carrying out among 135microfilariemia patients who were divided into three groups In Xiping county,Henan province,China.The result shows a marked therapeutic efficacy.The microfilaria counts decrease and become negative at the rate of 89.5% in the8th month and 93.5% in the 12th month after the treatment.Compared with the oral administration this method is More effective and has no side effectsduring the therapy.