采用ＴｄＲ同步化的方法，分析了人小肠癌转移腹水细胞系ＨＩＣＭＡ的核型，发现该细胞系染色体数目主要分布于５２～５６条之间，众数为５４条；染色体畸变复杂，在近５０％的分裂相中存在一条端着丝粒染色体，ＧＴＧ显带表明该染色体为正常５号染色体去掉整个短臂而成．对染色体畸变与细胞癌变的关系进行了讨论． Using TdR synchronization method, the karyotype of HICMA, a metastatic small cell carcinoma of ascites cell line, was analyzed. It was found that the number of chromosomes in this cell line was mainly distributed between 52-56, with a mode number of 54; chromosome aberrations were complex and were nearly 50. There is a telomeric chromosome in the dividing phase of %, and the GTG banding shows that the chromosome is removed from the normal chromosome 5 and the entire short arm is removed. The relationship between chromosome aberrations and cell carcinogenesis was discussed.