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目的:探讨新生儿ABO溶血病与O型血孕妇血清IgG抗体相关性。方法:选取在我院检查分娩的200例O型血产妇及其分娩新生儿,其丈夫血型为A、B或AB,孕妇22-35岁,胎次1-3胎,将夫妇RhD阴性排除。分析新生儿ABO溶血病与孕妇血清IgG抗体相关性。结果:在O型血200例孕妇中,丈夫为A型88例,B型82例,AB型30例。随孕妇产前IgG抗A(B)血型抗体效价经检测升高,统计新生儿溶血病,有增高趋势,呈正相关。结论:新生儿ABO溶血病与O型血孕妇血清IgG抗体效价呈正相关,可对各项数据测定,以预测新生儿溶血病,做到早期预防,以降低不良事件发生率,保障患儿出生质量。
Objective: To investigate the correlation between neonatal ABO hemolytic disease and serum IgG antibodies in O-pregnant women. Methods: A total of 200 O-type maternal mothers and their newborn babies were examined in our hospital. The husband’s blood group was A, B or AB, pregnant women aged 22-35 and parity 1-3 were excluded. Analysis of neonatal ABO hemolytic disease and serum IgG antibody in pregnant women. Results: Of the 200 pregnant women with type O blood, 88 were type A, 82 were type B, and 30 were type AB. With the pregnant women prenatal IgG anti-A (B) blood group antibody titer increased, statistics of neonatal hemolytic disease, there is an increasing trend, was positively correlated. Conclusion: There is a positive correlation between neonatal ABO hemolytic disease and serum IgG antibody titer in O-pregnant women, which can be used to predict the newborn hemolytic disease so as to prevent it early, so as to reduce the incidence of adverse events and ensure the birth of children quality.