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目的:探讨癫癎与睡眠呼吸暂停综合征(SAS)的相互关系,观察SAS的治疗对癫癎发作的影响。方法:从39例癫癎患者中筛选出可能合并SAS的病例进行多道睡眠图(PSG)监测,对确诊为SAS的中-重度患者行经鼻持续气道正压通气治疗(nCPAP)。结果:39例癫癎患者中有18例(46％)合并有SAS,且合并SAS的患者癫癎发作频率较高,平均为0．82次／月,与单纯癫癎患者的平均0．28次／月相比,明显升高(P<0．01)。经nCPAP治疗,癫癎发作频率减少至平均0．35次／月,与治疗前相比差异有显著意义(P<0．01)。结论:成人癫癎患者合并SAS发生率较高,SAS可加重癫癎的发作,治疗并存的SAS可提高对癫癎发作的控制力度,改善癫癎患者的生活质量。
Objective: To investigate the relationship between epilepsy and sleep apnea syndrome (SAS) and to observe the effect of SAS treatment on epileptic seizures. Methods: Thirty-nine patients with epilepsy were screened for possible polysomnography (PSG) in patients with SAS. Nasal continuous positive airway pressure (nCPAP) was performed in moderate-severe patients diagnosed with SAS. RESULTS: Eighteen (46%) of 39 epilepsy patients had SAS, and patients with SAS had a higher frequency of epileptic seizures with an average of 0.82 bpm, compared with an average of 0.28 in patients with epilepsy Times / month was significantly higher (P <0.01). After nCPAP treatment, epileptic seizure frequency reduced to an average of 0.35 times / month, compared with the pre-treatment difference was significant (P <0.01). Conclusions: The incidence of SAS complicated by adult epilepsy is high. SAS can exacerbate epilepsy. The coexistence of SAS improves the control of epileptic seizures and improves the quality of life of epileptic patients.